TREFFIC Workflow Diagram

Example: 1-44835-44867-AAAT, 1-370632-370648-TTTC

Prediction Instructions: please enter the LocusId of the TR locus to predict. The system will generate detailed webpage and PDF report. The LocusId can be obtained from trexplorer-catalog and TRAD database. LocusId Format: Chromosome-StartPosition-EndPosition-RepeatMotif

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About TREFFIC
  • • TREFFIC is a webserver that provides effect and pathogenicity prediction for user-submitted tandem repeats.
  • • TREFFIC requires users to submit the locus ID of a tandem repeat. Locus IDs can be obtained from the trexplorer-catalog and our TRAD database.
  • • TREFFIC leverages STRAS and RExPRT to predict the pathogenicity of tandem repeats.
  • • The basic information and gene annotation for tandem repeats provided by TREFFIC are sourced from the trexplorer-catalog and our TRAD database.
  • • The allele frequency data for tandem repeats provided by TREFFIC comes from Illumina 174k polymorphic TRs in 1kGP, Polymorphic TRs in 78 T2T assemblies, and TR-Atlas.
  • • We grant free access to all users of this website, including those engaged in commercial activities, to utilize the data, tools, and results it provides.
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